Alcohol Withdrawal Treatment | Do You Need it Before Quitting Booze?

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Alcohol Withdrawal Syndrome | Karen-Ann Clarke | Ausmed Lectures

The effects of heavy alcohol consumption may have an effect on the central nervous system (CNS). This session looks at this potentially lethal condition of alcohol withdrawal syndrome (AWS), also known as delirium tremens or the ‘DTs’.
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Psychoactive Drugs: pharmacology, intoxication, withdrawal, and treatment

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This is a brief video on psychoactive drugs, including the pharmacology of these drugs, intoxication symptoms, withdrawal symptoms, and relevant treatments.

Errata: error at 3:27; misspoke, should have said “agonize” not “antagonize”; proper word listed on slide.

I created this presentation with Google Slides.
Image were created or taken from Wikimedia Commons
I created this video with the YouTube Video Editor.

Anti addiction medications
1. cocaine
2. crack cocaine
3. methylphenidate (Ritalin)
4. ephedrine
5. MDMA (Ecstasy)
6. mescaline (cactus)
7. LSD blotter
8. psilocybin mushroom (Psilocybe cubensis)
9. Salvia divinorum
10. diphenhydramine (Benadryl)
11. Amanita muscaria mushroom
12. Tylenol 3 (contains codeine)
13. codeine with muscle relaxant
14. pipe tobacco
15. bupropion (Zyban)
16. cannabis
17. hashish
Depressants / sedatives
Alcohol, barbiturates, benzodiazepines
MoA: enhancement of GABA receptor
Intoxication: incoordination, ataxia, slurred speech, euphoria, nystagmus, attention impairment, behavior inhibition, coma, blackouts, AST = 2*ALT
Hypotension, respiratory depression → benzos and barbs
Treatment: flumazenil for benzo OD, supportive for others
Withdrawal: hallucinations, seizures, hypertension, nausea, sweating, insomnia, anxiety, agitation, tremors
Muscle cramps, twitches, tachycardia → benzos and barbs
Delirium tremens (2-4 days after last drink)→ fluctuating consciousness, high HR, seizures, tremors, anxiety
Treatment: benzodiazepines
Can be fatal

Heroin, prescription pain meds (oxycodone, hydrocodone, etc)
MoA: agonize opioid receptor, especially mu subtype
Intoxication: motor slowness, slurred speech, euphoria, impaired attention and sedation, miosis, respiratory depression
Treatment: naloxone, naltrexone (opioid antagonists)
Withdrawal: depression/anxiety, diarrhea, cramps, sweating, piloerection, pupillary dilation, yawning, muscle aches
Treatment: supportive for pain and GI distress; methadone and buprenorphine (weaker agonists) can help
Not fatal
Heroin and oxycodone are most widely abused opioids → responsible for many deaths
Depressants / sedatives
Cannabinoids (marijuana)
Hallucinogens (LSD)
Dissociatives (PCP)
Anti addiction medications

Cocaine, amphetamines, methamphetamines, MDMA (ecstasy), cathinone (bath salts), caffeine, nicotine
Cocaine → block norepi and DA reuptake
Amphetamine → increase synaptic [norepi] and [DA]
Nicotine → agonize PNS/CNS cholinergic receptors
Caffeine → enhance DA effect by blocking ADO receptors
Amphetamines → behavioral (grandiose, euphoric, hypervigilant, paranoia, agitation); autonomic (inc BP/HR, chills, sweating, n/v)
Cocaine → add hallucinations of bugs on skin
Treatment: lorazepam (anxiety); haloperidol (psychosis); vitals
Amphetamines/cocaine → appetite, low HR, depression, fatigue
Nicotineappetite, low HR, dysphoria, anxiety, irritability
Caffeine mild dysphoria, headaches, anxiety
Treatment: supportive
Marijuana, hashish, synthetic blends (e.g., K2, spice)
MoA: delta-5-tetrahydrocannabinol (THC) binds to cannabinoid receptor, which inhibits adenylate cyclase and cAMP production
Intoxication: conjunctivitis, dry mouth, high BP/HR, appetite, euphoria, hallucinations at high doses, agitation
Treatment: lorazepam for agitation
Withdrawal: irritability, agitation, insomnia, nausea
Treatment: supportive
Unnecessary because not fatal
Social implications: maybe amotivational syndrome, gateway drug
Physiological changes: low testosterone in men, decreased ovulation in females, low birth weights in neonates, increased neonatal malformations
Medical form (dronabinol) used as supportive addition to with chemo (antiemetic) or AIDS treatment (stimulate appetite)

LSD (acid), psilocybin (shrooms), mescaline (peyote)
MoA: LSD activates serotonin receptors in the limbic system, neocortex, and brainstem
Intoxication: hallucinations, delusions, mydriasis, tachycardia, sweating, ataxia, tremor
Euphoria, paranoia → psilocybin
Psychosis, flashbacks → LSD
Treatment: lorazepam for agitation, haloperidol for psychosis
Withdrawal: none
PCP, ketamine
MoA: both PCP and ketamine block glutamate NMDA receptors
Ketamine is used as an anesthetic (NMDA antagonist)
Intoxication: dissociation, hallucinations, impulsivity, analgesia, often violent behavior, high BP/HR, miosis, nystagmus, delusions, seizures
Benzodiazepines and antipsychotics → PCP
Monitor for serotonin syndrome and rhabdomyolysis
Alcohol addiction
Disulfiram (blocks aldehyde dehydrogenase)
Acamprosate (analog of GABA, NMDA receptor antagonist)
Naltrexone (opioid antagonist)
Endogenous opioid pathways play a key role in pathway that leads to reinforcement for alcohol addiction
Opioid addiction
Naltrexone (opioid antagonist)
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At Home Drug & Alcohol Withdrawal, Outpatient Medical Detox — Drug Rehab Advisor

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Located in the heart of the Embarcadero district, Foundations San Francisco offers comprehensive, confidential, compassionate outpatient treatment in a convenient urban setting. Flexible daytime and evening programs address addiction and any co-occurring mental health issues simultaneously in a supportive atmosphere where substance abuse is recognized as a disease. Patients are treated with dignity and respect as the staff focuses on each individual’s unique needs.

Our program is located in the Embarcadero building on a quiet street in beautiful downtown San Francisco. Everything takes place in the same building: process groups, individual sessions, random drug testing, and holistic offerings, such as yoga, acupuncture and massage therapy. You experience all of this while surrounded by soothing water views that include the San Francisco Bay and the Golden Gate Bridge. Parking, which is at a premium in the city, is also provided on-site.

Foundations Recovery Network’s mission is to be the leader in evidence-based, integrated treatment for co-occurring mental health and substance use disorders through clinical services, education and research.

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The Stages of Alcohol Withdrawal

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In this video, I discuss the stages of alcohol withdrawal, including the timelines for mild, moderate, and severe withdrawal. I also cover the root causes of alcohol withdrawal, along with some methods for shortening post-acute withdrawal from alcohol.

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Chris Scott started Fit Recovery in 2014 to help others benefit from his experience in beating alcohol addiction. Fit Recovery has helped thousands of people fill in the missing gaps that aren’t often covered extensively in traditional recovery programs, giving valuable guidance on nutrition, diet, exercise, and lifestyle.



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The actor revealed he recently completed another stint in rehab. Here’s a look at his history with alcohol addiction.

what “mild” methadone withdrawal looks like at 2mg

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There were two videos I filmed today. I chose to put this one out. The other one I have stored and will release one year or so from now, potentially longer. We all know I don’t have feelings lol. That video was too much. After taking a breath, I filmed this.

In this video I am going through “mild” methadone withdrawal. For those who are unfamiliar with my “story”, I’ve been in the clinic for several years (I always accidentally say eight, forgive me.) since 2011. My highest dose was 160mg. I started my “detox” from 25mg in October of 2017.

I didn’t think I’d feel any noticeable effects. I promised when I told my story here it’d be real. But positive. I’m unsure which this is. I’m having these effects as I’m typing this. I apologize, but this is just how it is at the moment (as you’re probably like what) haha. Thank you for following my journey.

Visible Symptoms In This Video:
Restless Legs
Insomnia yet exhausted (you’ll see what I mean)
Stumbling Over Words
Mood Swings

Other non visible withdrawal symptoms I talk about in here.
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Heroin withdrawal day 5

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Here is a video I cut when I was on day 5 of my heroin withdrawal detox. I hope you enjoy my story as well… I’ve been sober for 3 and a half years.

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Heroin Withdrawal: What Going Cold Turkey Feels Like

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This is what detox from heroin really feels like from someone who had lived it.

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